We thank Dr. Evangelatos for his interest in the guideline and his efforts to provide further clarity to this clinical scenario. During the guideline process, the voting panel thoroughly discussed many of these aspects of hypogammaglobulinemia during rituximab treatment that Dr. Evangelatos has adeptly described.

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回复：用利妥昔单抗治疗的类风湿关节炎患者的低丙种球蛋白血症：我们应该换用生物吗？

我们感谢 Evangelatos 博士对该指南的兴趣以及他为进一步阐明这一临床情况所做的努力。在指南过程中，投票小组彻底讨论了 Evangelatos 博士熟练描述的利妥昔单抗治疗期间低丙种球蛋白血症的许多方面。