Functional redundancy of the premotor network in hemispherotomy patients,Annals of Clinical and Translational Neurology

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Functional redundancy of the premotor network in hemispherotomy patients
Annals of Clinical and Translational Neurology ( IF 5.3 ) Pub Date : 2021-08-04 , DOI: 10.1002/acn3.51427
Conrad C Prillwitz ₁ , Bastian David ₁ , Gottfried Schlaug ₂ , Thomas Deller ₃ , Johannes Schramm ₄ , Robert Lindenberg ₅ , Elke Hattingen ₆ , Bernd Weber ₇ , Rainer Surges ₁ , Christian E Elger ₁ , Theodor Rüber _{1,

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Affiliation

Department of Epileptology, University of Bonn Medical Center, Bonn, Germany.
Stroke Recovery Laboratory, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
Institute of Clinical Neuroanatomy, Neuroscience Center, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Medical Faculty, University of Bonn, Bonn, Germany.
Department of History, Philosophy and Ethics of Medicine, Center for Health and Society, Heinrich-Heine-University, Düsseldorf, Germany.
Department of Neuroradiology, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Institute of Experimental Epileptology and Cognition Research, University of Bonn Medical Center, Bonn, Germany.
Department of Neurology, Epilepsy Center Frankfurt Rhine-Main, Goethe-University Frankfurt, Frankfurt am Main, Germany.
Center for Personalized Translational Epilepsy Research (CePTER), Goethe-University Frankfurt, Frankfurt am Main, Germany.

Using multimodal imaging, we tested the hypothesis that patients after hemispherotomy recruit non-primary motor areas and non-pyramidal descending motor fibers to restore motor function of the impaired limb.

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