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Clinical and radiographic factors involved in achieving a hematoma evacuation rate of more than 70% through minimally invasive catheter drainage for spontaneous intracerebral hemorrhage
Journal of Clinical Neuroscience ( IF 1.9 ) Pub Date : 2021-08-05 , DOI: 10.1016/j.jocn.2021.07.038
Ji Hee Kim 1 , Heui Seung Lee 1 , Jun Hyong Ahn 1 , Jae Keun Oh 1 , Joon Ho Song 1 , In Bok Chang 1
Affiliation  

Although stereotactic or neuronavigation-guided hematoma drainage for spontaneous intracerebral hemorrhage (ICH) is widely used, its clinical efficacy and factors for predictive results remain to be fully elucidated. This study sought to determine the efficacy of hematoma evacuation for spontaneous ICH, in addition to the factors affecting it. We retrospectively reviewed patients who underwent stereotactic or neuronavigation-guided catheter insertion for spontaneous ICH at our institute between April 2010 and December 2019. We identified and compared the clinical and radiographic factors between groups according to the hematoma evacuation rate of 70%. Logistic regression analyses were performed to identify factors affecting hematoma evacuation. We investigated whether the hematoma evacuation rate was associated with patient survival. A total of 95 patients who underwent stereotactic or neuronavigation-guided catheter insertion and hematoma drainage for spontaneous ICH were included. A multivariate analysis indicated that a hematoma volume of 30–60 cm3 (odds ratio [OR] = 8.064, 95% confidence interval [CI] = 2.285–28.468, P = 0.001), blend sign (OR = 6.790, 95% CI = 1.239–37.210, P = 0.027), diabetes (OR = 0.188, 95% CI = 0.041–0.870, P = 0.032), and leukocytosis (OR = 3.061, 95% CI = 1.094–8.563, P = 0.033) were significantly associated with a higher hematoma evacuation. The mean hematoma evacuation rate in patients with 1-month mortality was lower than that in survivors (P = 0.051). Our study revealed that a hematoma volume of 30–60 cm3, the presence of a blend sign and leukocytosis, and the absence of diabetes are independent predictors that affect more than 70% of hematoma evacuations.



中文翻译:

自发性脑出血微创导尿管引流血肿清除率达70%以上的临床及影像学因素

尽管立体定向或神经导航引导的血肿引流治疗自发性脑出血 (ICH) 已被广泛使用,但其临床疗效和预测结果的因素仍有待充分阐明。本研究旨在确定血肿清除对自发性 ICH 的疗效,以及影响它的因素。我们回顾性分析了 2010 年 4 月至 2019 年 12 月期间在我们研究所接受立体定向或神经导航引导下导管插入治疗自发性 ICH 的患者。我们根据 70% 的血肿清除率确定并比较了组间的临床和影像学因素。进行逻辑回归分析以确定影响血肿清除的因素。我们调查了血肿清除率是否与患者存活率相关。共纳入 95 名因自发性 ICH 接受立体定向或神经导航引导的导管插入和血肿引流术的患者。多变量分析表明,血肿体积为 30-60 cm3(比值比 [OR] = 8.064,95% 置信区间 [CI] = 2.285-28.468,P = 0.001),混合征(OR = 6.790,95% CI = 1.239-37.210,P = 0.027),糖尿病(OR = 0.027) = 0.188,95% CI = 0.041–0.870,P = 0.032)和白细胞增多(OR = 3.061,95% CI = 1.094–8.563,P = 0.033)与较高的血肿清除率显着相关。1个月死亡率患者的平均血肿清除率低于幸存者(P = 0.051)。我们的研究表明,30-60 cm 3的血肿体积、混合征和白细胞增多的存在以及没有糖尿病是影响超过 70% 的血肿清除的独立预测因素。

更新日期:2021-08-05
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