Introduction: The aim of this was to describe the predictors of mortality related to COVID-19 infection and to evaluate the association between overweight, obesity, and clinical outcomes of COVID-19. Methods: We included the patients #x3e;18 years of age, with at least one positive SARS-CoV-2 reverse transcriptase-polymerase chain reaction. Patients were grouped according to body mass index values as normal weight #x3c;25 kg/m² (Group A), overweight from 25 to #x3c;30 kg/m² (Group B), Class I obesity 30 to #x3c;35 kg/m² (Group C), and ≥35 kg/m² (Group D). Mortality, clinical outcomes, laboratory parameters, and comorbidities were compared among 4 groups. Results: There was no significant difference among study groups in terms of mortality. Noninvasive mechanical ventilation requirement was higher in group B and D than group A, while it was higher in Group D than Group C (Group B vs. Group A [p = 0.017], Group D vs. Group A [p = 0.001], and Group D vs. Group C [p = 0.016]). Lung involvement was less common in Group A, and presence of hypoxia was more common in Group D (Group B vs. Group A [p = 0.025], Group D vs. Group A [p #x3c; 0.001], Group D vs. Group B [p = 0.006], and Group D vs. Group C [p = 0.014]). The hospitalization rate was lower in Group A than in the other groups; in addition, patients in Group D have the highest rate of hospitalization (Group B vs. Group A [p #x3c; 0.001], Group C vs. Group A [p #x3c; 0.001], Group D vs. Group A [p #x3c; 0.001], Group D vs. Group B [p #x3c; 0.001], and Group D vs. Group C [p = 0.010]). Conclusion: COVID-19 patients with overweight and obesity presented with more severe clinical findings. Health-care providers should take into account that people living with overweight and obesity are at higher risk for COVID-19 and its complications.
Obes Facts

中文翻译：

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肥胖在预测 COVID-19 临床结果中的作用

简介：目的是描述与 COVID-19 感染相关的死亡率的预测因素，并评估超重、肥胖和 COVID-19 临床结果之间的关联。方法：我们纳入了患者 #x3e；18 岁，至少有一个 SARS-CoV-2 逆转录酶-聚合酶链反应阳性。患者根据体重指数值分组为正常体重#x3c；25 kg/m ²（A组），超重25至#x3c；30 kg/m ²（B组），I级肥胖30至#x3c； 35 kg/m ² (C组)，≥35 kg/m ² (D组)。比较 4 组的死亡率、临床结果、实验室参数和合并症。结果：在死亡率方面，研究组之间没有显着差异。B 组和 D 组的无创机械通气需求高于 A 组，而 D 组高于 C 组（B 组与 A 组 [ p = 0.017]，D 组与 A 组 [ p = 0.001]， D 组与 C 组 [ p = 0.016]）。A 组肺部受累较少见，D 组更常见缺氧（B 组与 A 组 [ p = 0.025]，D 组与 A 组 [ p #x3c; 0.001]，D组与 A组）。 B 组 [ p = 0.006]，D 组与 C 组 [ p= 0.014]）。A组住院率低于其他组；此外，D组患者的住院率最高（B组与A组[ p #x3c; 0.001]，C组与A组[ p #x3c; 0.001]，D组与A组[ p #x3c；0.001]，D 组与 B 组 [ p #x3c；0.001]，D 组与 C 组 [ p = 0.010]）。结论：超重和肥胖的 COVID-19 患者表现出更严重的临床表现。卫生保健提供者应考虑到，超重和肥胖患者感染 COVID-19 及其并发症的风险更高。
肥胖事实