The green synthesis of silver nanoparticles (AgNPs) using plant extract, the cost-effective solution, and the abundance and environmental issue have been gaining much attention to scientists. Ganoderma lucidum (GL) commonly known as Lingzhi in Chinese and Reishi in Japanese, with a proven anticancer benefit, is discovered in the buffer zone of Bach Ma National Park, Nam Dong district, Thua Thien Hue province. In this work, the AgNPs were synthesized in a simple and effective biochemical reduction process using GL which is one of the biological organisms, as a reducing and stable agent. The optimum conditions of various experimental parameters such as pH, reaction time, concentration, and temperature were investigated. Obtained AgNPs were characterized by UV-Vis, FTIR, SEM, energy-dispersive X-ray spectroscopy (EDX), X-ray diffraction (XRD), and transmission electron microscopy (TEM). The effects of AgNP/GL materials and GL aqueous extraction on the antiproliferative activities of HepG2 and MCF-7 cells were studied. The novel AgNP/GL-based multicomponent suspension is a key compound that could find a good application in the medical and pharmaceutical sciences.

中文翻译：

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使用灵芝提取物通过环保工艺合成生物银纳米颗粒及其治疗诊断应用评价

使用植物提取物绿色合成银纳米粒子 (AgNPs)、具有成本效益的解决方案以及丰度和环境问题已引起科学家们的广泛关注。灵芝(GL) 在中文中通常称为灵芝，在日语中称为灵芝，在 Thua Thien Hue 省 Nam Dong 区 Bach Ma 国家公园的缓冲区中发现，具有经证实的抗癌功效。在这项工作中，AgNPs 是在简单有效的生化还原过程中合成的，使用 GL 是生物有机体之一，作为还原剂和稳定剂。研究了各种实验参数的最佳条件，如pH、反应时间、浓度和温度。获得的AgNPs通过UV-Vis、FTIR、SEM、能量色散X射线光谱（EDX）、X射线衍射（XRD）和透射电子显微镜（TEM）进行表征。研究了 AgNP/GL 材料和 GL 水提物对 HepG2 和 MCF-7 细胞抗增殖活性的影响。