Phage-encoded cationic antimicrobial peptide required for lysis,Journal of Bacteriology

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Phage-encoded cationic antimicrobial peptide required for lysis
Journal of Bacteriology ( IF 2.7 ) Pub Date : 2021-08-02 , DOI: 10.1128/jb.00214-21
Ashley Holt _{1,

2} , Jesse Cahill _{1,

2} , Jolene Ramsey _{1,

2} , Cody Martin _{1,

2} , Chandler O'Leary _{1,

2} , Russell Moreland _{1,

2} , Lori T Maddox _{1,

2} , Thushara Galbadage ₃ , Riti Sharan ₃ , Preeti Sule ₃ , Jeffrey D Cirillo ₃ , Ry Young _{1,

2}

Affiliation

Most phages of Gram-negative hosts encode spanins for disruption of the outer membrane, the last step in host lysis. However, bioinformatic analysis indicates that ∼15% of these phages lack a spanin gene, suggesting they have an alternate way of ...

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