Non-small-cell lung cancer (NSCLC) is one of the most common fatal cancers in the world. Although the treatment of NSCLC has been significantly improved, there is still an unmet need to identify novel targets for developing therapeutic agents and diagnostic/prognostic markers. The aim of this study is explore the role and underlying mechanism of the epithelial splicing regulatory protein (ESRP1) in the development and progression of NSCLC.

中文翻译：

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ESRP1作为非小细胞肺癌的预后因子与Twist的EMT转录因子有关

非小细胞肺癌（NSCLC）是世界上最常见的致命癌症之一。尽管 NSCLC 的治疗已得到显着改善，但仍然需要确定用于开发治疗剂和诊断/预后标志物的新靶点。本研究旨在探讨上皮剪接调节蛋白（ESRP1）在非小细胞肺癌发生发展中的作用及其潜在机制。