Fe₃O₄@XAD-16 has been used as adsorbent for magnetic dispersive solid phase extraction of Cu(II) as with 1- (2-pyridylazo) -2-naphthol (PAN) complex prior to flame atomic absorption spectrometric detection of copper. The effects of important parameters affecting extraction efficiency such as pH, adsorbent amount, eluent concentration and volume, model solution volume and ultrasonic bath time on magnetic solid phase extraction were studied in detail. The optimum pH for the extraction of Cu (II) was 6.0. The enrichment factor was 25. The accuracy of the extraction method was determined by the analysis of HR-1 (river sediment) and TMDA-53.3 (lake water) certified reference materials. The method was applied to determination of copper contents of food and water samples.

Fe ₃ O ₄ @XAD-16 已被用作吸附剂，在铜的火焰原子吸收光谱检测之前，与 1- (2-吡啶偶氮) -2-萘酚 (PAN) 络合物一样，对 Cu(II) 进行磁分散固相萃取. 详细研究了影响萃取效率的重要参数如pH值、吸附剂用量、洗脱液浓度和体积、模型溶液体积和超声浴时间对磁固相萃取的影响。提取铜 (II) 的最佳 pH 值为 6.0。富集因子为25。提取方法的准确性通过对HR-1（河流沉积物）和TMDA-53.3（湖水）有证标准物质的分析来确定。该方法适用于食品和水样中铜含量的测定。