Objectives

The study aimed to assess the possible effects of corneal cross-linking (CXL) on contact lens (CL) fitting in patients with progressive keratoconus who initially had CL intolerance.

Methods

A retrospective review was performed of the medical records of patients who had stopped CL wear due to discomfort prior to CXL and who were fitted with CLs after CXL. All eyes were evaluated pre- and 1, 6, 12, 24 months postoperatively. Data collected included pre- and post-CXL refraction, corneal topographic data, uncorrected visual acuity, and best-corrected visual acuity (BCVA). CL comfort was evaluated using the Likert scale post-CXL.

Results

A total of 20 eyes from 14 patients were included in the study. Preoperative Kmax values significantly decreased by 2.8 D at 6 months and by 4.1 D at 12 months after CXL (p < 0.001 for both). CLs were prescribed on average 12 ± 2.5 months after CXL. The mean duration of successful CL wear was 10.4 ± 2.8 months during the follow-up period. Subjective CL comfort scores were satisfactory post-CXL.

Conclusion

CXL not only halts the progression of keratoconus but may also improve CL tolerance by providing a more regular shaped cornea in these patients. Ongoing corneal topographic changes in the late postoperative period after CXL may have a positive effect on CL fitting.

中文翻译：

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渐进性圆锥角膜角膜交联后隐形眼镜配戴改善

目标

该研究旨在评估角膜交联 (CXL) 对最初患有 CL 不耐受的进行性圆锥角膜患者配戴隐形眼镜 (CL) 的可能影响。

方法

对在 CXL 之前由于不适而停止 CL 佩戴以及在 CXL 之后安装 CL 的患者的医疗记录进行了回顾性审查。所有眼睛在术前和术后 1、6、12、24 个月进行评估。收集的数据包括 CXL 屈光前后、角膜地形图数据、未矫正视力和最佳矫正视力 (BCVA)。CL 舒适度 使用 李克特量表在 CXL 后进行评估。

结果

该研究共包括来自 14 名患者的 20 只眼睛。术前 Kmax 值在 6 个月时显着下降 2.8 D，在 CXL 后 12 个月时显着下降 4.1 D（两者的 p < 0.001）。CXL 后平均 12 ± 2.5 个月开具 CL。在随访期间，成功佩戴 CL 的平均持续时间为 10.4 ± 2.8 个月。主观 CL 舒适度评分在 CXL 后令人满意。

结论

CXL 不仅可以阻止圆锥角膜的进展，还可以通过为这些患者提供更规则形状的角膜来提高 CL 耐受性。CXL 术后后期持续的角膜地形变化可能对 CL 拟合产生积极影响。