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Biomarkers in the diagnosis of wounds infection: An analytical perspective
Trends in Analytical Chemistry ( IF 11.8 ) Pub Date : 2021-08-03 , DOI: 10.1016/j.trac.2021.116405
Fátima A.R. Mota , Sarah A.P. Pereira , André R.T. S. Araújo , Marieta L.C. Passos , M.Lúcia M.F. S. Saraiva

Infection is one of the most serious complications that can occur in wounds. Biomarkers can be used as a tool directly related to infection. So, herein current methods and new approaches for the determination of wound infection, based on biomarkers, were compared and discussed. In this review, it is highlighted the different enzymatic biomarkers related to wound infection, and how they can be used for early detection of the same. It also aims to compile the different analytical methods and describe the potential of each one.

The global and critical analysis research made it possible to perceive that of all the biomarkers studied, the enzymes demonstrated great potential, through the comparison with all biomarkers, since they allow the detection of infection in very early stages, and so a previous diagnostic and treatment.



中文翻译:

伤口感染诊断中的生物标志物:分析视角

感染是伤口中可能发生的最严重的并发症之一。生物标志物可用作与感染直接相关的工具。因此,本文比较和讨论了基于生物标志物确定伤口感染的当前方法和新方法。在这篇综述中,重点介绍了与伤口感染相关的不同酶促生物标志物,以及它们如何用于早期检测。它还旨在汇编不同的分析方法并描述每种方法的潜力。

全球和批判性分析研究使人们有可能认识到,在所有研究的生物标志物中,酶通过与所有生物标志物的比较显示出巨大的潜力,因为它们允许在非常早期的阶段检测感染,因此可以进行先前的诊断和治疗.

更新日期:2021-08-20
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