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Angiogenic potential of mesenchymal stem cells derived from patients with diabetes seeded on decellularized micro fragments
Journal of Diabetes and its Complications ( IF 2.9 ) Pub Date : 2021-08-03 , DOI: 10.1016/j.jdiacomp.2021.108001 Assaf Assis 1 , Yechiel N Gellman 2 , Avivit Cahn 3 , Amir Haze 2 , Sandra Camargo 1 , Eduardo Mitrani 4
中文翻译:
来自糖尿病患者的间充质干细胞在脱细胞微碎片上的血管生成潜力
更新日期:2021-09-06
Journal of Diabetes and its Complications ( IF 2.9 ) Pub Date : 2021-08-03 , DOI: 10.1016/j.jdiacomp.2021.108001 Assaf Assis 1 , Yechiel N Gellman 2 , Avivit Cahn 3 , Amir Haze 2 , Sandra Camargo 1 , Eduardo Mitrani 4
Affiliation
Mesenchymal stem cells (MSCs) are a potential source of angiogenic factors which may promote wound healing in poorly vascularized diabetic foot ulcers. We demonstrate that MSCs of patients with diabetic foot ulcers seeded on decellularized micro-fragments transcribe and secrete angiogenic factors in amounts comparable to MSCs derived from healthy individuals.
中文翻译:
来自糖尿病患者的间充质干细胞在脱细胞微碎片上的血管生成潜力
间充质干细胞 (MSCs) 是血管生成因子的潜在来源,可促进血管化不良的糖尿病足溃疡的伤口愈合。我们证明,糖尿病足溃疡患者的 MSCs 接种在脱细胞微片段上,其转录和分泌血管生成因子的量与来自健康个体的 MSCs 相当。