Introduction The COVID-19 pandemic has seen the introduction of important public health measures to minimise the spread of the virus. We aim to identify the impact government restrictions and hospital-based infection control procedures on ST elevation myocardial infarction (STEMI) care during the COVID-19 pandemic. Methods Patients meeting ST elevation criteria and undergoing primary percutaneous coronary intervention from 27 March 2020, the day initial national lockdown measures were announced in Ireland, were included in the study. Patients presenting after the lockdown period, from 18 May to 31 June 2020, were also examined. Time from symptom onset to first medical contact (FMC), transfer time and time of wire cross was noted. Additionally, patient characteristics, left ventricular ejection fraction, mortality and biochemical parameters were documented. Outcomes and characteristics were compared against a control group of patients meeting ST elevation criteria during the month of January. Results A total of 42 patients presented with STEMI during the lockdown period. A significant increase in total ischaemic time (TIT) was noted versus controls (8.81 hours (±16.4) vs 2.99 hours (±1.39), p=0.03), with increases driven largely by delays in seeking FMC (7.13 hours (±16.4) vs 1.98 hours (±1.46), p=0.049). TIT remained significantly elevated during the postlockdown period (6.1 hours (±5.3), p=0.05), however, an improvement in patient delays was seen versus the control group (3.99 hours (±4.5), p=0.06). There was no difference seen in transfer times and door to wire cross time during lockdown, however, a significant increase in transfer times was seen postlockdown versus controls (1.81 hours (±1.0) vs 1.1 hours (±0.87), p=0.004). Conclusion A significant increase in TIT was seen during the lockdown period driven mainly by patient factors highlighting the significance of public health messages on public perception. Additionally, a significant delay in transfer times to our centre was seen postlockdown. All data for the purpose of this study as stored in fully anonymised document available from the corresponding author on reasonable request.

中文翻译：

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在 COVID-19 大流行期间符合 ST 段抬高标准的爱尔兰患者的审查

简介 COVID-19 大流行已经采取了重要的公共卫生措施，以尽量减少病毒的传播。我们的目标是确定在 COVID-19 大流行期间政府限制和基于医院的感染控制程序对 ST 段抬高型心肌梗死 (STEMI) 护理的影响。方法 符合 ST 段抬高标准并从 2020 年 3 月 27 日（爱尔兰宣布初步国家封锁措施的那一天）开始接受初级经皮冠状动脉介入治疗的患者被纳入研究。还对 2020 年 5 月 18 日至 6 月 31 日锁定期后就诊的患者进行了检查。记录从症状出现到第一次医疗接触 (FMC) 的时间、转移时间和导线交叉时间。此外，患者特征、左心室射血分数、死亡率和生化指标记录。成果和特点反对月份会议期间ST段抬高标准的患者对照组进行对比。结果在锁定期间总共42例存在STEMI。在总缺血时间（TIT）甲显著上升与对照（8.81小时（±16.4）对2.99小时（±1.39）中，p = 0.03），并在寻求FMC由延迟很大程度上带动增加（7.13小时（±16.4） VS1.98小时（±1.46）中，p = 0.049）。TIT在postlockdown期间保持显著升高（6.1小时（±5.3）中，p = 0.05），然而，在患者的延迟的改善被认为相对于对照组（3.99小时（±4.5）中，p = 0.06）。目前还没有任何传输时间和门看到锁定期间线径时间差，但是，在传输时间则显著上升看出postlockdown与对照（1.81小时（±1.0）VS1.1小时（±0.87）中，p = 0.004）。在TIT结论一个显著上升过程中，主要通过强调公共健康信息对公众认知的意义患者因素驱动的锁定期被看见。此外，在传输次显著延迟到我们中心看到postlockdown。这项研究的目的所有数据存储可从合理要求相应的作者完全匿名文件内。在封锁后，我们看到转移到我们中心的时间显着延迟。用于本研究目的的所有数据都存储在完全匿名的文件中，可根据合理要求从相应的作者处获得。在封锁后，我们看到转移到我们中心的时间显着延迟。用于本研究目的的所有数据都存储在完全匿名的文件中，可根据合理要求从相应的作者处获得。