The phytochemical study was done on the leaves of Gambeya lacourtiana. This plant has been used in traditional medicine to treat of different ailments such as uterine heamorrhage, metritis and other vaginal infections. Chromatographic fractionation and purification on the leaves crude extract afforded lupeol acetate (1), lupenone (2), lupeol (3), taraxerol (4) stigmasterol (5), erythrodiol (6), chamaedrydiol (7), methyl pheophorbide-a (8), corosolic acid (9), tormentic acid (10), epicatechin (11) and 22-dihydrospinasterol 3-O-β-D-glucopyranoside (12). The structures of compounds 1–12 were elucidated on the basis of 1D and 2D NMR, mass spectrometric and the spectroscopic data as well as comparison with the literature. Compounds 4, 7–10 and 12 were isolated for the first time from Gambeya genus. Crude extract, fractions and compounds 6–12 were evaluated for their antibacterial activity. Methyl pheophorbide-a (8) demonstrated moderate activity against Salmonella typhi CPC with MIC values of 62.5 μg/mL. The chemophenetic significance of these compounds is also discussed.

植物化学研究是在Gambeya lacourtiana的叶子上进行的。这种植物已在传统医学中用于治疗不同的疾病，如子宫出血、子宫炎和其他阴道感染。色谱分离和纯化在叶子上的粗提取物，得到羽扇豆醇乙酸酯（1），羽扇豆烯酮（2），羽扇豆醇（3），蒲公英赛醇（4）豆甾醇（5），高根二醇（6），chamaedrydiol（7），甲基脱镁叶绿-A（8 )、科罗索酸( 9 )、tormentic酸( 10 )、表儿茶素( 11 )和22-二氢菠菜甾醇3-O - β - D-吡喃葡萄糖苷( 12 )。化合物的结构1 - 12分别鉴定一维和二维NMR，质谱和光谱数据的基础上，以及与文献比较上。化合物4，7 - 10和12中分离的第一次从Gambeya属。评估了粗提取物、馏分和化合物6-12的抗菌活性。Methyl pheophorbide-a ( 8 ) 对伤寒沙门氏菌表现出中等活性CPC 的 MIC 值为 62.5 μg/mL。还讨论了这些化合物的化学表观意义。