Certain cyclic sulfates (e.g. 23) together with various of their precursor sulfites (e.g. 21 and 22) have been prepared from the corresponding chiral, non-racemic bicyclo[2.2.2]octane-2,3-diols (e.g. 20). Such diols are obtained by engaging the corresponding enzymatically derived and enantiomerically enriched or homochiral cis-1,2-dihydrocatechol (e.g. 10) or certain derivatives in either inter- or intra-molecular Diels–Alder cycloaddition reactions. Other functionalities present within the title compounds can be chemoselectively manipulated without adversely affecting the associated sulfate residues.

中文翻译：

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某些衍生自手性、非外消旋和多取代双环 [2.2.2] 辛烷-2,3-二醇的官能化环状硫酸盐的合成、结构表征和化学选择性操作

某些环状硫酸盐（例如23）及其各种前体亚硫酸盐（例如21和22）已从相应的手性、非外消旋双环 [2.2.2] 辛烷-2,3-二醇（例如20）制备。这种二醇是通过在分子间或分子内 Diels-Alder 环加成反应中加入相应的酶衍生和对映体富集或同手性顺式-1,2-二氢邻苯二酚（例如10）或某些衍生物而获得的。标题化合物中存在的其他官能团可以进行化学选择性操作，而不会对相关的硫酸盐残基产生不利影响。