ABSTRACT

Background

There is little knowledge about rest-activity cycles (RAC) in patients with severe-acquired brain injury (sABI) during early in-hospital rehabilitation. This study aimed to investigate if patients with sABI displayed unconsolidated RACs at the beginning of in-hospital rehabilitation, and how these changed over time.

Methods

This study was a prospective observational study. All patients consecutively admitted to one ward were screened for eligibility. We recorded accelerometric activity for 20 days. The Daytime Activity Ratio (DAR) of activity between daytime (7–22) and the total activity during the entire day was calculated and used to estimate consolidation.

Results

Fifty-five patients were screened and 20 patients were included. Complete day 1 & 2 data was obtained on 18 patients. Fifty-six percentage of these had a consolidated RAC at the beginning of rehabilitation. On day 19 & 20, complete data could be obtained from 15 patients, 80% of these had consolidation of RAC. When comparing these a significant mean increase of 5.8% 95%CI(0.52; 11.01) in DAR was found p < .05, and the model of all data also showed a significant increase in median DAR over time p < .01.

Conclusion

RAC consolidation improves over time in patients admitted for in-hospital early neurorehabilitation.

中文翻译：

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重度获得性脑损伤患者休息-活动周期的评估：一项观察性研究

摘要

背景

在院内早期康复期间，对重度获得性脑损伤 (sABI) 患者的休息-活动周期 (RAC) 知之甚少。本研究旨在调查 sABI 患者在院内康复开始时是否表现出未巩固的 RAC，以及这些如何随时间变化。

方法

本研究是一项前瞻性观察性研究。对连续入住一个病房的所有患者进行资格筛选。我们记录了 20 天的加速度计活动。计算白天 (7-22) 与全天总活动之间的活动的白天活动比率 (DAR) 并用于估计巩固。

结果

筛选了 55 名患者，其中包括 20 名患者。获得了 18 名患者的完整第 1 天和第 2 天数据。其中 56% 在康复开始时有一个综合的 RAC。在第 19 天和第 20 天，可以从 15 名患者中获得完整数据，其中 80% 有 RAC 巩固。当比较这些时，发现 DAR 平均显着增加 5.8% 95%CI(0.52; 11.01) p < .05，并且所有数据的模型也显示 DAR 中位数随时间显着增加p < .01。

结论

在住院早期神经康复治疗的患者中，RAC 巩固随着时间的推移而改善。