Gastric accommodation: Physiology, diagnostic modalities, clinical relevance, and therapies,Neurogastroenterology & Motility

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Gastric accommodation: Physiology, diagnostic modalities, clinical relevance, and therapies
Neurogastroenterology & Motility ( IF 3.5 ) Pub Date : 2021-08-01 , DOI: 10.1111/nmo.14213
Liz Febo-Rodriguez ₁ , Bruno P Chumpitazi _{2,

3} , Andrew C Sher ₄ , Robert J Shulman _{2,

3}

Affiliation

Gastric accommodation is an essential gastric motor function which occurs following ingestion of a meal. Impaired gastric fundic accommodation (IFA) is associated with dyspeptic symptoms. Gastric accommodation is mediated by the vagal pathway with several important physiologic factors such as duodenal nutrient feedback playing a significant role. IFA has been described as a pathophysiologic factor in several gastrointestinal disorders including functional dyspepsia, diabetic gastropathy, post-Nissen fundoplication, postsurgical gastrectomy, and rumination syndrome. Modalities for gastric accommodation assessment include gastric barostat, intragastric meal distribution via scintigraphy, drinking tests (eg, water load), SPECT, MRI, 2D and 3D ultrasound, and intragastric high-resolution manometry. Several treatment options including sumatriptan, buspirone, tandospirone, ondansetron, and acotiamide may improve symptoms by increasing post-meal gastric volume.

中文翻译：

胃适应：生理学、诊断方式、临床相关性和治疗

胃调节是一种重要的胃运动功能，发生在进食后。胃底调节（IFA）受损与消化不良症状有关。胃调节是由迷走神经通路介导的，其中一些重要的生理因素如十二指肠营养反馈起着重要作用。IFA 已被描述为几种胃肠道疾病的病理生理因素，包括功能性消化不良、糖尿病性胃病、尼森胃底折叠术、术后胃切除术和反刍综合征。胃调节评估的方式包括胃恒压器、通过闪烁显像的胃内膳食分布、饮水测试（例如，水负荷）、SPECT、MRI、2D和3D超声以及胃内高分辨率测压。几种治疗选择，包括舒马曲坦，

更新日期：2021-08-01

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