The present study was designed to demonstrate the potential of supercritical extracts from Achillea millefolium and Rosa canina herbal dust, and their mixtures, as a source of valuable aromatic and lipophilic compounds. The supercritical carbon dioxide extraction (SFE-CO₂) was performed at the pressures from 10-30 MPa, providing the total extraction yields (EY) in the range from 0.12 to 10.57%, being the highest when pure R. canina herbal dust was extracted using SFE-CO₂ at 30 MPa for 5 h. Chemical profiles of SFE-CO₂ extracts were determined by GC-MS and GC-FID. Oxygenated monoterpenes and sesquiterpene hydrocarbons were among the most abundant compounds in the extracts produced from A. millefolium and mixtures with a higher share of A. millefolium herbal dust. In the same mixtures, at the pressure of 10 MPa, a cosolvent effect was observed, which provided enhanced extraction of eucalyptol. The major tocol in A. millefolium and R. canina mixtures was α-tocopherol (589.49 mg/L). By investigating the influence of extraction pressure, it has been determined that higher compound recoveries could be obtained at lower pressures. The results clearly demonstrate that SFE-CO₂ extracts of the A. millefolium and R. canina and their herbal dust mixtures are a promising source of valuable compounds to be used in pharmaceutical formulations.

本研究的目的是证明从超临界提取物的潜在洋蓍草和狗蔷薇草药灰尘，和它们的混合物，作为有价值的芳族和亲脂性化合物的来源。超临界二氧化碳萃取 (SFE-CO ₂ ) 在 10 - 30 MPa的压力下进行，提供的总萃取率 (EY) 在 0.12 至 10.57% 的范围内，当纯R. canina草药粉使用 SFE-CO ₂在 30 MPa 下提取5 小时。SFE-CO _{2 的}化学特性提取物通过 GC-MS 和 GC-FID 测定。氧化单萜和倍半萜烃类是在从制备的提取物中最丰富的化合物中A.蓍的混合物和与更高份额A.蓍草药灰尘。在相同的混合物中，在 10 MPa 的压力下，观察到共溶剂效应，这提供了增强的桉油精提取。A. millefolium和R. canina混合物中的主要母育酚是 α-生育酚 (589.49 mg/L)。通过研究萃取压力的影响，已经确定可以在较低压力下获得更高的化合物回收率。结果清楚地表明，SFE-CO ₂的提取物A.蓍和R. canina及其草药粉末混合物是用于药物制剂的有价值化合物的有希望的来源。