Heavy metals (HMs) are affected by natural and human activities and contaminate the soil environment, endanger plant growth and pose a serious threat to the ecosystem. HMs interfere with plant metabolism and some protein activities and cause oxygen stress. Plants combat excess HMs in the environment through a complex array of biological activities (such as antioxidant mechanisms, chelation, and regionalization of HM ions). Metabolomics is an emerging technique utilized for the qualitative and quantitative analysis of all low-molecular-weight metabolites that is now widely used in toxicology, disease diagnosis, plant research and other fields and has become an important component of systems biology. This paper reviews the progress and current status of metabolomics research on plants under HM stress and introduces plant detoxification and phytoremediation mechanisms.

重金属（HMs）受自然和人类活动的影响，污染土壤环境，危害植物生长，对生态系统构成严重威胁。HMs 干扰植物代谢和一些蛋白质活动并引起氧胁迫。植物通过一系列复杂的生物活动（例如抗氧化机制、螯合和 HM 离子的区域化）来对抗环境中过量的 HMs。代谢组学是一种用于对所有低分子量代谢物进行定性和定量分析的新兴技术，目前广泛应用于毒理学、疾病诊断、植物研究等领域，已成为系统生物学的重要组成部分。