Supercritical CO₂ and a mango leaves extract were used to impregnate calcium-sodium alginate wound dressings. Two methods of impregnation were developed: batch and semi-continuous supercritical impregnation. The influence of parameters such as pressure, temperature and depressurization rate on the impregnation process was studied in terms of the antioxidant capacity of the samples and the impregnation load of polyphenols present in the mango leaves extract. The higher load of mango polyphenols and strong antioxidant capacity were obtained in batch mode at 30 MPa, 35 °C and at fast depressurization rate. Semi-continuous mode behaved in a similar way but with lower results according to obtained impregnation percentages in the assayed conditions. The antioxidant capacity of the processed samples was verified by DPPH method, and to confirm the presence of the antioxidant particles and their distribution on the matrix, the processed alginate wound dressings were studied by UPLC-MS and Scanning Electron Microscopy (SEM).

超临界 CO ₂和芒果叶提取物用于浸渍藻酸钙钠伤口敷料。开发了两种浸渍方法：间歇和半连续超临界浸渍。根据样品的抗氧化能力和芒果叶提取物中存在的多酚的浸渍负荷，研究了压力、温度和减压速率等参数对浸渍过程的影响。在 30 MPa、35 °C 和快速降压。半连续模式以类似的方式表现，但根据在测定条件下获得的浸渍百分比，结果较低。通过 DPPH 方法验证加工样品的抗氧化能力，并通过 UPLC-MS 和扫描电子显微镜 (SEM) 研究加工后的藻酸盐伤口敷料，以确认抗氧化剂颗粒的存在及其在基质上的分布。