Journal of Industrial and Engineering Chemistry ( IF 5.9 ) Pub Date : 2021-07-31 , DOI: 10.1016/j.jiec.2021.07.041 Jia Liu 1 , Shuxia Wang 1 , Lei Jiang 1 , Wei Shao 1
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Kanamycin covalently grafted onto regenerated bacterial cellulose (RBC) membranes were constructed to prepare novel antimicrobial BC membranes. The prepared kanamycin grafted RBC membrane exhibits nanoporous three-dimensional network structure with a large surface area and high porosity. The antibacterial activity was explored and the result shows that the kanamycin grafted RBC membrane displays excellent antibacterial activity towards E. coli, C. albicans and S. aureus without any kanamycin leaching. Furthermore, MTT assay was carried out and the result demonstrates that the kanamycin grafted RBC membrane displays good biocompatibility.
中文翻译：
具有非浸出活性的抗菌细菌纤维素膜的制备和表征
构建了共价接枝到再生细菌纤维素 (RBC) 膜上的卡那霉素，以制备新型抗菌 BC 膜。制备的卡那霉素接枝红细胞膜呈现纳米多孔三维网络结构，具有大表面积和高孔隙率。对抗菌活性进行了研究，结果表明卡那霉素接枝的红细胞膜对大肠杆菌、白色念珠菌和金黄色葡萄球菌显示出优异的抗菌活性，而没有任何卡那霉素浸出。此外，进行了MTT测定，结果表明卡那霉素接枝的RBC膜显示出良好的生物相容性。
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