Known as elite suppressors, some individuals infected with HIV show no symptoms and barely detectable virus levels years after initial infection, despite never having received treatment. Joel N. Blankson has spent much of his career studying elite suppressors, who represent less than 1% of people with HIV, with the hope that they may serve as models for developing new treatments. Blankson is a professor of medicine at the Johns Hopkins University School of Medicine, and his laboratory has demonstrated that elite suppressors’ natural control of HIV is not due to differences or defects in the viral strains infecting them. PNAS recently spoke to Blankson about this phenomenon.

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与 Joel N. Blankson 的 QnA

一些感染 HIV 的人被称为精英抑制者，尽管从未接受过治疗，但在初次感染数年后，他们没有表现出任何症状，而且病毒水平几乎检测不到。乔尔·N·布兰克森 (Joel N. Blankson) 的大部分职业生涯都在研究精英抑制者，他们只占 HIV 感染者的不到 1%，希望它们可以作为开发新疗法的模型。布兰克森是约翰霍普金斯大学医学院的医学教授，他的实验室已经证明，精英抑制者对 HIV 的自然控制并不是由于感染它们的病毒株的差异或缺陷。PNAS 最近就这一现象与布兰克森进行了交谈。