Clostridioides difficile R20291 is the most studied PCR-Ribotype 027 isolate. The two predominant lineages of this hypervirulent strain, however, exhibit substantive phenotypic differences and possess genomes that differ by a small number of nucleotide changes. It is important that the source of R20291 is taken into account in research outcomes.

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什么是朋友之间的 SNP：艰难梭菌 R20291 的谱系会影响研究成果

艰难梭菌R20291 是研究最多的 PCR-核糖型 027 分离株。然而，这种高毒力菌株的两个主要谱系表现出实质性的表型差异，并拥有因少量核苷酸变化而不同的基因组。在研究结果中考虑 R20291 的来源很重要。