Sickle cell anemia (SCA) results in numerous adverse effects on the brain, including neurocognitive dysfunction. Hydroxyurea has been utilized extensively for management of SCA, but its effects on brain function have not been established.

中文翻译：

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羟基脲对镰状细胞性贫血患儿脑功能的影响

镰状细胞性贫血 (SCA) 会对大脑产生许多不良影响，包括神经认知功能障碍。羟基脲已广泛用于治疗 SCA，但尚未确定其对脑功能的影响。