Acute kidney injury (AKI) is common after cardiac surgery requiring cardiopulmonary bypass. Renal hypoxia may precede clinically detectable AKI. We compared the efficacy of two indices of renal hypoxia, (i) intraoperative urinary oxygen tension (UPO₂) and (ii) the change in plasma erythropoietin (pEPO) during surgery, in predicting AKI. We also investigated whether the performance of these prognostic markers varies with preoperative patient characteristics.

中文翻译：

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术中肾缺氧和心脏手术相关急性肾损伤的风险

急性肾损伤 (AKI) 在需要体外循环的心脏手术后很常见。肾脏缺氧可能先于临床可检测到的 AKI。我们比较了肾缺氧的两个指标（i）术中尿氧分压（UPO ₂）和（ii）手术期间血浆促红细胞生成素（pEPO）的变化在预测 AKI 方面的功效。我们还调查了这些预后标志物的表现是否随术前患者特征而变化。