The main objective of the present paper is to report two studies on mathematical and computational techniques used to model the behaviour of the aorta in the human cardiovascular system. In this paper, an account of the design and implementation of two distinct models is presented: a Windkessel model and an agent-based model. Windkessel model represents the left heart and arterial system of the cardiovascular system in the physiological domain. The agent-based model offers a simplified account of arterial behaviour by randomly generating arterial parameter values. This study has described the mechanism how and when the left heart contracts and pumps the blood out of the aorta, and it has taken the Windkessel model one step further. The results of this study show that the dynamics of the aorta can be explored in each modelling approaches as proposed and implemented by our research group. It is thought that this study will contribute to the literature in terms of development of the Windkessel model by considering its timing and redesigning it with digital electronics perspective. PDF  XML

中文翻译：

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利用 Windkessel 和基于代理的建模对主动脉进行行为表示

本论文的主要目的是报告两项关于用于模拟人类心血管系统中主动脉行为的数学和计算技术的研究。在本文中，介绍了两种不同模型的设计和实现：Windkessel 模型和基于代理的模型。Windkessel 模型在生理领域代表了心血管系统的左心和动脉系统。基于代理的模型通过随机生成动脉参数值提供了对动脉行为的简化说明。这项研究描述了左心如何以及何时收缩并将血液泵出主动脉的机制，并使 Windkessel 模型更进了一步。这项研究的结果表明，可以在我们研究小组提出和实施的每种建模方法中探索主动脉的动力学。人们认为，通过考虑 Windkessel 模型的时间并从数字电子学的角度重新设计它，这项研究将有助于在 Windkessel 模型的发展方面的文献。PDF XML