The role of occupational stress on male fertility is understudied. We examined associations between male occupational stress and fecundability. We used data from Pregnancy Study Online (PRESTO), a North American preconception cohort study. At baseline (2013-2019), male participants aged ≥ 21 years completed a baseline questionnaire on employment status, hours worked per week, time of day worked (daytime, evening, nights, and changing or rotating shifts), and job title. We used the O*NET occupational database to rate independence by job title. Female partners were followed via bimonthly follow-up questionnaires for 12 months or until pregnancy. We restricted analyses to 1,818 couples attempting conception for ≤ 6 cycles at enrollment. We used proportional probabilities regression to estimate fecundability ratios (FRs) and 95% confidence intervals (CIs). The FR comparing unemployed with employed men was0.84 (95% CI: 0.62-1.14). Among employed men, FRs and 95% CIs for evening shift work, night shift work, and rotating shift work were 0.89 (95% CI: 0.68-1.17), 0.94 (95% CI: 0.66-1.33), and 0.91 (95% CI: 0.75-1.11) relative to daytime shift work. The FR for any nondaytime shift work was 0.91 (95% CI: 0.78-1.07). Total work hours (long or short) and job independence scores were not appreciably associated with fecundability. In conclusion, working nondaytime shifts and being unemployed were associated with slightly decreased fecundability. However, the variability in these estimates was substantial and the results were reasonably consistent with chance. Little association was observed for other occupation measures. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

中文翻译：

---

工作时间、轮班工作和工作范围与生育能力之间的关联：一项先入为主的队列研究。

职业压力对男性生育能力的影响尚未得到充分研究。我们检查了男性职业压力与生育能力之间的关联。我们使用了来自北美孕前队列研究 Pregnancy Study Online (PRESTO) 的数据。在基线时（2013-2019 年），年龄≥21 岁的男性参与者完成了一份关于就业状况、每周工作时间、一天中的工作时间（白天、晚上、晚上以及换班或轮班）和职位的基线问卷。我们使用 O*NET 职业数据库按职位对独立性进行评级。女性伴侣通过双月随访问卷进行随访 12 个月或直至怀孕。我们将分析限制在 1,818 对登记时尝试受孕 ≤ 6 个周期的夫妇。我们使用比例概率回归来估计生育率 (FRs) 和 95% 置信区间 (CIs)。失业人员与就业人员比较的 FR 为 0.84（95% CI：0.62-1.14）。在就业男性中，夜班工作、夜班工作和轮班工作的 FR 和 95% CI 分别为 0.89（95% CI：0.68-1.17）、0.94（95% CI：0.66-1.33）和 0.91（95% CI：0.75-1.11) 相对于白班工作。任何非白天轮班工作的 FR 为 0.91（95% CI：0.78-1.07）。总工作时间（长或短）和工作独立性分数与生育能力没有明显关联。总之，非白天轮班工作和失业与生育能力略有下降有关。然而，这些估计的可变性很大，结果与偶然性相当一致。观察到其他占领措施几乎没有关联。（PsycInfo 数据库记录 (c) 2022 APA，保留所有权利）。