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Promises of Lipid-based Drug Delivery Systems in the Management of Breast Cancer
Current Pharmaceutical Design ( IF 2.6 ) Pub Date : 2021-11-30 , DOI: 10.2174/1381612827666210728104318
Nagarani Thotakura 1 , Madan M Gupta 2 , Jitendra S Rajawat 3 , Kaisar Raza 1
Affiliation  

Breast cancer is one of the leading types among the common non-cutaneous malignancies in women. All the curative methods available for its treatment are minimal due to their toxicity issues and dose-related side effects. Various evolving nanotechnology techniques displayed the opportunity to target breast cancer. One such delivery system is lipid-based drug delivery systems (LDDS). This concept is constrained only for the laboratory scale should be shifted to the industrial level targeting the nanomedicine with clinical benefits. This work tried to portray the advancements in the LDDS along with the lipid-based excipients, advantages, disadvantages and applications. It even helped in highlighting the recently developed lipid-based nanocarriers for breast cancer management.



中文翻译:

基于脂质的药物输送系统在乳腺癌治疗中的前景

乳腺癌是女性常见的非皮肤恶性肿瘤中的主要类型之一。由于毒性问题和与剂量相关的副作用,所有可用于治疗的治疗方法都很少。各种不断发展的纳米技术显示了靶向乳腺癌的机会。一种这样的递送系统是基于脂质的药物递送系统(LDDS)。这一概念仅限于实验室规模,应转向工业水平,以具有临床益处的纳米药物为目标。这项工作试图描绘 LDDS 的进步以及基于脂质的赋形剂、优点、缺点和应用。它甚至有助于突出最近开发的用于乳腺癌治疗的基于脂质的纳米载体。

更新日期:2021-11-19
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