Use of systemic hormone therapy has been positively associated with development of dementia. Little is known about the dose-dependent effect of vaginal estradiol on dementia risk.

中文翻译：

---

阴道雌激素与痴呆症的关系：一项全国性的基于人群的研究

全身激素治疗的使用与痴呆症的发展呈正相关。关于阴道雌二醇对痴呆风险的剂量依赖性影响知之甚少。