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The effect of simple heat treatment on apatite formation on grit-blasted/acid-etched dental Ti implants already in clinical use
Journal of Biomedical Materials Research Part B: Applied Biomaterials ( IF 3.2 ) Pub Date : 2021-07-29 , DOI: 10.1002/jbm.b.34915
Ayano Ogura 1, 2 , Seiji Yamaguchi 3 , Phuc Thi Minh Le 3, 4 , Kayoko Yamamoto 1 , Michi Omori 1 , Kazuya Inoue 1 , Nahoko Kato-Kogoe 1 , Yoichiro Nakajima 1 , Hiroyuki Nakano 1 , Takaaki Ueno 1 , Tomohiro Yamada 2 , Yoshihide Mori 2
Affiliation  

Grit-blasted/acid-etched titanium dental implants have a moderately roughened surface that is suitable for cell adhesion and exhibits faster osseointegration. However, the roughened surface does not always maintain stable fixation over a long period. In this study, a simple heat treatment at 600°C was performed on a commercially available dental Ti implant with grit-blasting/acid-etching, and its effect on mineralization capacity was assessed by examining apatite formation in a simulated body fluid (SBF). The as-purchased implant displayed a moderately roughened surface at the micrometer scale. Its surface was composed of titanium hydride accompanied by a small amount of alumina particles derived from the grit-blasting. Heat treatment transformed the titanium hydride into rutile without evidently changing the surface morphology. The immersion in SBF revealed that apatite formed on the heated implant at 7 days. Furthermore, apatite formed on the Ti rod surface within 1 day when the metal was subjected to acid and heat treatment without blasting. These indicate that apatite formation was conferred on the commercially available dental implant by simple heat treatment, although its induction period was slightly affected by alumina particles remaining on the implant surface. The heat-treated implant should achieve stronger and more stable bone bonding due to its apatite formation.

中文翻译:

简单热处理对已在临床使用的喷砂/酸蚀牙科钛种植体上磷灰石形成的影响

喷砂/酸蚀钛牙种植体具有适度粗糙的表面,适合细胞粘附并表现出更快的骨整合。然而,粗糙的表面并不总是能长期保持稳定的固定。在这项研究中,对市售的带有喷砂/酸蚀的牙科钛种植体进行了 600°C 的简单热处理,并通过检查模拟体液 (SBF) 中的磷灰石形成来评估其对矿化能力的影响. 购买的植入物在微米级显示出适度粗糙的表面。其表面由氢化钛组成,并伴有少量来自喷砂处理的氧化铝颗粒。热处理使钛氢化物转变为金红石,而表面形貌没有明显改变。浸泡在 SBF 中显示在 7 天时在加热的植入物上形成了磷灰石。此外,在没有喷砂的情况下对金属进行酸和热处理,在 1 天内在钛棒表面形成磷灰石。这些表明磷灰石的形成是通过简单的热处理在市售的牙科植入物上形成的,尽管其诱导期受到植入物表面上残留的氧化铝颗粒的轻微影响。由于其磷灰石的形成,热处理的植入物应该实现更强和更稳定的骨结合。这些表明磷灰石的形成是通过简单的热处理在市售的牙科植入物上形成的,尽管其诱导期受到植入物表面上残留的氧化铝颗粒的轻微影响。由于其磷灰石的形成,热处理的植入物应该实现更强和更稳定的骨结合。这些表明磷灰石的形成是通过简单的热处理在市售的牙科植入物上形成的,尽管其诱导期受到植入物表面上残留的氧化铝颗粒的轻微影响。由于其磷灰石的形成,热处理的植入物应该实现更强和更稳定的骨结合。
更新日期:2021-07-29
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