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Cryptococcosis and unexpected death
Forensic Science, Medicine and Pathology ( IF 1.8 ) Pub Date : 2021-07-29 , DOI: 10.1007/s12024-021-00400-1
Abbie Tu 1 , Roger W. Byard 1
Affiliation  

Cryptococcosis is a fungal disease caused predominantly by Cryptococcus neoformans and Cryptococcus gatti. It is most often found in immunocompromised individuals and has quite protean and chronic manifestations affecting all body systems. The unexpected death of a 22-year-old man with cryptococcal meningoencephalitis demonstrates, however, that it may have a fulminant course in previously well individuals. Also present at autopsy was a toruloma of the upper lobe of the right lung. Delays in clinical diagnoses, confusion with tuberculosis and precipitate clinical deterioration may mean that cases will be encountered unexpectedly during medicolegal autopsies.



中文翻译:

隐球菌病和意外死亡

隐球菌病是一种真菌疾病,主要由新型隐球菌加蒂隐球菌引起。它最常见于免疫功能低下的个体,并具有影响所有身体系统的多变和慢性表现。然而,一名患有隐球菌脑膜脑炎的 22 岁男子的意外死亡表明,它可能在以前健康的个体中具有暴发性病程。尸检时还发现右肺上叶圆环瘤。临床诊断的延误、与肺结核的混淆以及导致临床恶化可能意味着在法医尸检过程中会意外遇到病例。

更新日期:2021-07-29
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