The preparation of value-added products is an effective way to reuse waste cotton fabrics (WCFs). Seven kinds of choline chloride (ChCl)-based deep eutectic solvents (DESs) were rapidly formed and characterized. Performances of these ChCl-based DESs were evaluated in terms of degradation of WCFs to 5-hydroxymethylfurfural (5-HMF) without any additional catalyst. The degradation was characterized by high-performance liquid chromatography (HPLC) and scanning electron microscopy (SEM) method. The results showed that the DESs formed by ChCl and p-toluene sulfonic acid (p-TSA) had the best effect in converting WCFs. Moreover, the stability of 5-HMF in the as-obtained DESs was also investigated. The highest 5-HMF yield was 10.20 % at 100 °C, with a reaction time of 90 min, and the molar ratio of hydrogen bond acceptor (HBA) to hydrogen bond donor (HBD) was 1:1.3 in ChCl/p-TSA DESs system without a catalyst. The investigated DESs system offers a good alternative compared to the available WCFs degradation methods, considering its cost-efficiency, environmental, and operability aspects. Therefore, the green and environmentally friendly synthesis of 5-HMF from cellulose materials (WCFs) could be an effective method to realize the high-value utilization of waste textiles, having an important theoretical significance and practical value.

高附加值产品的制备是废棉织物（WCFs）再利用的有效途径。七种基于氯化胆碱 (ChCl) 的低共熔溶剂 (DES) 被快速形成和表征。在没有任何额外催化剂的情况下，根据 WCF 降解为 5-羟甲基糠醛 (5-HMF) 来评估这些基于 ChCl 的 DES 的性能。通过高效液相色谱（HPLC）和扫描电子显微镜（SEM）方法表征降解。结果表明，由 ChCl 和对甲苯磺酸形成的 DESs ( p-TSA) 在转换 WCF 方面效果最好。此外，还研究了 5-HMF 在所获得的 DES 中的稳定性。在 100 °C 时，5-HMF 的最高产率为 10.20 %，反应时间为 90 min，氢键受体 (HBA) 与氢键供体 (HBD) 的摩尔比在 ChCl/ p -TSA 中为 1:1.3没有催化剂的DESs系统。考虑到其成本效益、环境和可操作性方面，所研究的 DES 系统提供了与可用的 WCF 降解方法相比的良好替代方案。因此，以纤维素材料（WCFs）为原料绿色环保合成5-HMF是实现废弃纺织品高价值化利用的有效方法，具有重要的理论意义和实用价值。