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Relationship of Gensini score with retinal vessel diameter and arteriovenous ratio in senile CHD
Open Life Sciences ( IF 1.7 ) Pub Date : 2021-07-16 , DOI: 10.1515/biol-2021-0068
Ning Wang 1 , Changsen Liang 2
Affiliation  

Background This study aimed to find the correlation of Gensini score with retinal vessel diameter and arteriovenous ratio in elderly patients with coronary heart disease (CHD). Methods This study included 120 senile CHD patients as the CHD group and 100 healthy individuals as the normal group (NG). Gensini score was used to evaluate the severity of coronary artery lesions. Central retinal artery equivalents (CRAE), central retinal venular equivalents (CRVE), and arteriovenous ratio (AVR) were measured. Results CHD group has lower CRAE and AVR than NG, while higher CRVE was observed in NG. CRAE and AVR in UAP (unstable angina pectoris) and AMI (acute myocardial infarction) groups showed reduction (stable angina pectoris); however, enhanced CRVE and Gensini scores in UA and AMI groups were observed as compared to the SAP group. CRAE and AVR in moderate and severe groups were reduced to a greater extent compared to the mild groups, while enhanced CRVE and Gensini scores were observed more often in the severe group than the mild group. CRAE and AVR were negatively correlated with the Gensini score; however, CRVE was positively correlated with the Gensini score. Conclusion AVR is expected to be a noninvasive index to diagnose and predict senile CHD, which has a certain evaluation value. Diabetes, smoking history, and TC are independent risk factors of senile CHD.

中文翻译:

Gensini评分与老年冠心病视网膜血管直径及动静脉比值的关系

背景 本研究旨在探讨老年冠心病(CHD)患者Gensini评分与视网膜血管直径和动静脉比的相关性。方法本研究选取120例老年冠心病患者作为冠心病组,100名健康人作为正常组(NG)。Gensini评分用于评估冠状动脉病变的严重程度。测量了视网膜中央动脉当量 (CRAE)、视网膜中央小静脉当量 (CRVE) 和动静脉比 (AVR)。结果CHD组CRAE和AVR低于NG,而NG组CRVE较高。UAP(不稳定型心绞痛)和 AMI(急性心肌梗死)组的 CRAE 和 AVR 显示减少(稳定型心绞痛);然而,与 SAP 组相比,UA 和 AMI 组的 CRVE 和 Gensini 评分有所提高。与轻度组相比,中度和重度组的CRAE和AVR降低幅度更大,而在重度组中观察到的CRVE和Gensini评分高于轻度组。CRAE和AVR与Gensini评分呈负相关;然而,CRVE 与 Gensini 评分呈正相关。结论 AVR有望成为诊断和预测老年CHD的无创指标,具有一定的评价价值。糖尿病、吸烟史和 TC 是老年 CHD 的独立危险因素。结论 AVR有望成为诊断和预测老年CHD的无创指标,具有一定的评价价值。糖尿病、吸烟史和 TC 是老年 CHD 的独立危险因素。结论 AVR有望成为诊断和预测老年CHD的无创指标,具有一定的评价价值。糖尿病、吸烟史和 TC 是老年 CHD 的独立危险因素。
更新日期:2021-07-16
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