Combination of different antimalarials has become the popular method of care for malaria morbidity in conventional and traditional treatment approaches due to the need to increase the efficacy and reduce the selection of drug resistance. A worrisome concern is the critical gaps with regards to the information available on antimalarial herbal cocktails. This study presents cocktail herbal remedies in ethnomedicinal approaches to malaria treatment in Oyo and Ogun states, South West Nigeria. Ethnobotanical information on indigenous antimalarials used in combination remedies was collected from herbal practitioners using a semi-structured questionnaire. Findings showed majority of respondents treat malaria with combination herbal remedies. They sighted their beliefs and customs, the efficacy, affordability and availability of these herbs as reasons for their adoption of herbal medicines as their preferred mode of treating malaria. Enquiry revealed 26 sets of cocktail antimalarials from a variety of plant species. The plants and ingredients are extracted and used as decoction, infusion or steam baths. Oral route was the most popular mode of administration. Respondents reported they drink one to two medium-sized cups of the recipe on an average of two times daily within a duration of about 10 days. Herbal antimalarial remedies continue to be the popular treatments option in our localities. This study provides knowledge of the diverse ways respondents combine medicinal herbs and other local ingredients for malaria treatment. Pharmacological screening is urgently needed to validate their safety and efficacy in order to protect the health of our locals heavily relying on them to combat high burdens of malaria.

中文翻译：

---

尼日利亚西南部常用于治疗疟疾的民族植物鸡尾酒调查

由于需要提高疗效并减少耐药性的选择，不同抗疟药的组合已成为常规和传统治疗方法中治疗疟疾发病率的流行方法。一个令人担忧的问题是关于抗疟草药鸡尾酒的可用信息存在严重差距。本研究介绍了尼日利亚西南部奥约州和奥贡州采用民族医学方法治疗疟疾的鸡尾酒草药疗法。使用半结构化问卷从草药从业者那里收集了有关用于组合疗​​法的本土抗疟药的民族植物学信息。调查结果显示，大多数受访者使用联合草药疗法治疗疟疾。他们看到了他们的信仰和习俗，功效，这些草药的可负担性和可用性是他们采用草药作为治疗疟疾的首选方式的原因。调查显示了来自各种植物物种的 26 组鸡尾酒抗疟药。植物和成分被提取并用作煎剂、输液或蒸汽浴。口服途径是最流行的给药方式。受访者报告说，他们在大约 10 天的时间内平均每天两次喝一到两杯中等大小的食谱。草药抗疟药仍然是我们当地流行的治疗选择。这项研究提供了受访者将药草和其他当地成分结合用于治疗疟疾的多种方式的知识。