Abiotesting procedure that stipulates periodic (every 2 h) instrumental recording of changes in pH, redox potential, and electrical conductivity of a liquid growth medium incubated for 6 h at 37°C in the presence and absence of viable test microorganisms and test samples is described. Results of a comparative analysis performed using this method for the pro- and antibiotic activity against various representatives of human microbiota at various concentrations of aqueous plant extracts (PEs) obtained in different ways from 20 types of raw material are presented. The studies confirmed that the proposed method allows a much more rapid, objective, and informative evaluation (but less time- and material-consuming that standard visual methods of microbiological testing) of the impact of various samples of pharmacological and other products (such as PEs) on the dynamics of the vital activity of various microorganisms. It was also confirmed that the biological activity of PEs depends significantly on not only the raw materials and extraction method used to produce them but also the PE concentration, the duration of their interaction with the microorganisms, the type of microorganisms, etc. The results of the study can be used to develop formulations and to assess the properties of a new pharmaceutical and other products. In addition, the instrumental microbiological testing technique described and tested in this work can be used to monitor pro-and antibiotic properties of samples of various products already accepted for use.

描述了在 37°C 下在存在和不存在活的测试微生物和测试样品的情况下培养 6 小时的液体培养基的 pH、氧化还原电位和电导率变化的定期（每 2 小时）仪器记录的生物测试程序. 介绍了使用这种方法对以不同方式从 20 种原材料中获得的各种浓度的水性植物提取物 (PE) 的各种代表人类微生物群的前体和抗生素活性进行的比较分析的结果。研究证实，所提出的方法允许更加快速、客观、药理和其他产品（如 PE）的各种样品对各种微生物的生命活动动态的影响的信息评估（但比微生物测试的标准视觉方法花费的时间和材料更少）。还证实，PE 的生物活性不仅取决于生产它们的原材料和提取方法，还取决于 PE 的浓度、它们与微生物相互作用的持续时间、微生物的类型等。该研究可用于开发配方并评估新药物和其他产品的特性。此外，