Geographic, gender and seasonal variation of diabetes: a nationwide study among 1.4 million participants,The Journal of Clinical Endocrinology & Metabolism

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Geographic, gender and seasonal variation of diabetes: a nationwide study among 1.4 million participants
The Journal of Clinical Endocrinology & Metabolism ( IF 5.0 ) Pub Date : 2021-07-27 , DOI: 10.1210/clinem/dgab543
Yuanfeng Zhang _{1,

2} , Mingkun Tong ₃ , Bo Wang ₃ , Zumin Shi ₄ , Ping Wang _{5,

6} , Liming Li _{3,

6} , Yi Ning _{3,

7} , Tao Lu ₂

Affiliation

Abstract

Background

China experienced a rapid increase in the prevalence of diabetes.

Objectives

To assess the prevalence of diabetes among Chinese adults who attend preventive physical examination, and analyzed geographical and gender difference in seasonal variation of fasting blood glucose (FBG).

Methods

The study used data from 1,390,088 participants attending preventive health examination at 430 health screening centers in 220 cities. Diagnosis of diabetes and prediabetes were based on FBG and hemoglobinA_1c and self-report physician’s diagnosis. We calculated age and sex standardized prevalence of diabetes according to the sixth Chinese population census data in 2010. Geographical distribution of diabetes and prediabetes were displayed on the country map. FBG were analyzed to detect the seasonal variation adjusted for age and gender by geographic location.

Results

The standardized prevalence of diabetes was 8.70% (95% CI, 8.22%-9.19%), 10.7% in men and 6.61% in women. Among those with diabetes, 43.7% (95% CI, 40.9%-46.5%) were aware of their conditions and 38.5% (95% CI, 36.0%-41.1%) were treated. Only 49.3% (95% CI, 47.0%-51.6%) of treated patients achieved glycemic control. The mean level of FBG was higher in winter than summer and in the northern than the southern.

Conclusions

The prevalence of diabetes was high whilst the percentages of awareness, treatment and glycemic control were low among adults. Effective measures are needed to prevent and manage diabetes in China. Geographic and seasonal variation of diabetes should be considered for its prevention and control.

更新日期：2021-07-28

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