Alkaloid leonurine exerts anti-inflammatory effects via modulating MST1 expression in trophoblast cells,Immunity, Inflammation and Disease

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Alkaloid leonurine exerts anti-inflammatory effects via modulating MST1 expression in trophoblast cells
Immunity, Inflammation and Disease ( IF 3.1 ) Pub Date : 2021-07-28 , DOI: 10.1002/iid3.493
Fang Zong ₁ , Yingzi Zhao ₁

Affiliation

Pre-eclampsia (PE) is mainly attributed to the inflammation of trophoblast cells in pregnant women, which results in damage to the maternal organs and growth retardation of the fetus. Alkaloid leonurine (LNR) is a plant compound and has anti-inflammatory effects. Here we aimed to investigate the effects of LNR on human and mouse trophoblast cells and the underlying mechanisms.

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