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Protein nanocage-stabilized Pickering emulsions
Current Opinion in Colloid & Interface Science ( IF 8.9 ) Pub Date : 2021-07-28 , DOI: 10.1016/j.cocis.2021.101485
Sierin Lim 1 , Stefan Salentinig 2
Affiliation  

The utilization of surface-active engineered protein nanocages as stabilizers for emulsions provides avenues for the design of new tailor-made functional materials in various fields including food, pharmaceutical, and biotechnology. They can be used to codeliver bioactive molecules of different polarities in a tailored manner to the body, act as a platform for screening cells or enzymes, or function as targeted drug delivery systems. Knowledge on the mechanisms that underlie the protein nanocage-driven stabilization of emulsions and their colloidal structure can have direct implications for the rational design of the new advanced functional colloids.

This contribution summarizes the recent progress in protein nanocage-stabilized emulsions. It discusses the advances in the precision bioengineering of protein nanocages for emulsion design, highlights challenges in the characterization of structure and dynamics in these materials, and demonstrates selected applications in the field of functional food materials.



中文翻译:

蛋白质纳米笼稳定的 Pickering 乳液

利用表面活性工程蛋白质纳米笼作为乳液的稳定剂,为在食品、制药和生物技术等各个领域设计新的定制功能材料提供了途径。它们可用于以量身定制的方式将不同极性的生物活性分子共同递送至身体,充当筛选细胞或酶的平台,或充当靶向药物递送系统。了解蛋白质纳米笼驱动的乳液稳定性及其胶体结构的机制,可以对新型先进功能胶体的合理设计产生直接影响。

这一贡献总结了蛋白质纳米笼稳定乳液的最新进展。它讨论了用于乳液设计的蛋白质纳米笼精密生物工程的进展,突出了这些材料的结构和动力学表征方面的挑战,并展示了在功能性食品材料领域的选定应用。

更新日期:2021-09-10
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