Atypicalities in psychophysical thresholds for global motion processing have been reported in many neurodevelopmental conditions, including autism and dyslexia. Cross-syndrome comparisons of neural dynamics may help determine whether altered motion processing is a general marker of atypical development or condition-specific. Here, we assessed group differences in N2 peak amplitude (previously proposed as a marker of motion-specific processing) in typically developing (n = 57), autistic (n = 29) and dyslexic children (n = 44) aged 6–14 years, in two global motion tasks. High-density EEG data were collected while children judged the direction of global motion stimuli as quickly and accurately as possible, following a period of random motion. Using a data-driven component decomposition technique, we identified a reliable component that was maximal over occipital electrodes and had an N2-like peak at ~160 msec. We found no group differences in N2 peak amplitude, in either task. However, for both autistic and dyslexic children, there was evidence of atypicalities in later stages of processing that require follow up in future research. Our results suggest that early sensory encoding of motion information is unimpaired in dyslexic and autistic children. Group differences in later processing stages could reflect sustained global motion responses, decision-making, metacognitive processes and/or response generation, which may also distinguish between autistic and dyslexic individuals.

在包括自闭症和阅读障碍在内的许多神经发育疾病中，已经报道了全球运动处理的心理物理阈值的非典型性。神经动力学的交叉综合征比较可能有助于确定改变的运动处理是否是非典型发育的一般标志或特定条件。在这里，我们评估了 6-14 岁的典型发育 (n = 57)、自闭症 (n = 29) 和诵读困难儿童 (n = 44) 中 N2 峰值幅度（之前提出作为运动特异性处理的标志）的组差异，在两个全局运动任务中。收集高密度脑电图数据，同时儿童在一段时间的随机运动后尽可能快速准确地判断整体运动刺激的方向。使用数据驱动的组件分解技术，我们确定了一个可靠的组件，该组件在枕骨电极上最大，并且在约 160 毫秒时具有类似 N2 的峰值。在任一项任务中，我们发现 N2 峰值幅度没有组间差异。然而，对于自闭症和诵读困难的儿童，有证据表明在处理的后期阶段存在非典型性，需要在未来的研究中进行跟进。我们的研究结果表明，运动信息的早期感觉编码在阅读障碍和自闭症儿童中没有受到损害。后期处理阶段的群体差异可能反映持续的整体运动反应、决策、元认知过程和/或反应生成，这也可能区分自闭症和阅读障碍个体。对于自闭症和诵读困难的儿童，有证据表明在处理的后期阶段存在非典型性，需要在未来的研究中进行跟进。我们的研究结果表明，运动信息的早期感觉编码在阅读障碍和自闭症儿童中没有受到损害。后期处理阶段的群体差异可能反映持续的整体运动反应、决策、元认知过程和/或反应生成，这也可能区分自闭症和阅读障碍个体。对于自闭症和诵读困难的儿童，有证据表明在处理的后期阶段存在非典型性，需要在未来的研究中进行跟进。我们的研究结果表明，运动信息的早期感觉编码在阅读障碍和自闭症儿童中没有受到损害。后期处理阶段的群体差异可能反映持续的整体运动反应、决策、元认知过程和/或反应生成，这也可能区分自闭症和阅读障碍个体。