Inconsistent eradication rates for Helicobacter pylori have been reported worldwide with dual therapy, perhaps owing to the difference in dose administration and treatment duration. This retrospective study aimed to determine whether high-dose dual therapy (HDDT) with different regimens leads to different eradication rates. The study compares the efficacy and safety of HDDT 10-day vs 14-day and investigates the factors that might affect the eradication rates.

中文翻译：

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治疗幽门螺杆菌的 10 天和 14 天大剂量双联疗法：倾向评分匹配分析

世界范围内报告的双重治疗幽门螺杆菌根除率不一致，这可能是由于给药剂量和治疗持续时间的差异。这项回顾性研究旨在确定不同方案的高剂量双重治疗 (HDDT) 是否会导致不同的根除率。该研究比较了 HDDT 10 天与 14 天的疗效和安全性，并调查了可能影响根除率的因素。