Recombinant Pseudomonas bio-nanoparticles induce protection against pneumonic Pseudomonas aeruginosa infection,Infection and Immunity

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Recombinant Pseudomonas bio-nanoparticles induce protection against pneumonic Pseudomonas aeruginosa infection
Infection and Immunity ( IF 3.1 ) Pub Date : 2021-07-26 , DOI: 10.1128/iai.00396-21
Peng Li ₁ , Xiuran Wang ₁ , Xiangwan Sun ₁ , Jesse Cimino ₁ , Ziqiang Guan ₂ , Wei Sun ₁

Affiliation

To develop an effective Pseudomonas aeruginosa (PA) outer-membrane-vesicles (OMVs) vaccine, we eliminated multiple virulence factors from a wild-type P. aeruginosa PA103 strain (PA103) to generate a recombinant strain, PA-m14. The PA-m14 strain was ...

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