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A renal and hepatic toxicity analysis of remdesivir formulations: Does what is on the inside really count?
Antimicrobial Agents and Chemotherapy ( IF 4.9 ) Pub Date : 2021-07-26 , DOI: 10.1128/aac.01045-21
Sunish Shah 1, 2 , Tyler W Ackley 1 , Jeffrey E Topal 1, 3
Affiliation  

It has been postulated that the injectable solution formulation of remdesivir could be more nephrotoxic than the lyophilized powder since it contains twice as much sulfobutylether-β-cyclodextrin (SBECD). Therefore, we evaluated 1000 hospitalized patients ...

中文翻译:

瑞德西韦制剂的肾和肝毒性分析:里面的东西真的很重要吗?

据推测,瑞德西韦的注射液制剂可能比冻干粉更具肾毒性,因为它含有两倍的磺丁基醚-β-环糊精 (SBECD)。因此,我们评估了 1000 名住院患者...
更新日期:2021-09-12
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