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STEM CELLS ( IF 5.2 ) Pub Date : 2021-07-27 , DOI: 10.1002/stem.3222


Image depicts a potential approach to the perfusion of human brain organoids with an organ-on-chip device. A brain organoid is cultivated in a device with the fluid channels including vascular cells. The vascular cells may migrate and form vessel-like structures that bridge the fluid channel and the brain organoid. This kind of device succeeded in establishing vessel-like structures in the lung fibroblast spheroid.

中文翻译:

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图像描绘了一种使用片上器官设备灌注人脑类器官的潜在方法。在具有包括血管细胞在内的流体通道的装置中培养大脑类器官。血管细胞可能会迁移并形成连接流体通道和大脑类器官的血管状结构。这种装置成功地在肺成纤维细胞球体中建立了血管样结构。
更新日期:2021-07-27
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