ABSTRACT

Alginate coatings were fabricated by electrophoretic deposition (EPD) using alcohol (methanol, ethanol and isopropanol)-water mixtures at different ratios. Water electrolysis and so current density increased with water content and EPD time leading to the more bubbles in coatings. EPD rate increased with water amount due to the increase in concentration of H⁺ and Alg⁻ ions and reduction in solution viscosity. According to the results of kinetics, optical microscopy and corrosion analyses the coating deposited at 10 V for 1 min from the ethanolic solution with 60 vol.-% of water was selected as the optimum coating for in-vitro cell culture and antibacterial analyses. There was almost 30% rise in cell expansion for the sample with optimum coating after 7 days compared to the blank. Also, the coated sample showed antibacterial activity against Bacillus bacteria.

摘要

使用不同比例的醇（甲醇、乙醇和异丙醇）-水混合物通过电泳沉积 (EPD) 制造藻酸盐涂层。水电解和电流密度随着含水量和 EPD 时间的增加而增加，导致涂层中的气泡更多。由于 H ⁺和 Alg ^-离子浓度的增加以及溶液粘度的降低，EPD 速率随着水量的增加而增加。根据动力学、光学显微镜和腐蚀分析的结果，选择在 60 vol.-% 水的乙醇溶液中在 10 V 下沉积 1 min 的涂层作为体外的最佳涂层。细胞培养和抗菌分析​​。与空白相比，7 天后具有最佳涂层的样品的细胞扩增增加了近 30%。此外，涂层样品显示出对芽孢杆菌细菌的抗菌活性。