Electrochemical Dimethyl Sulfide-Mediated Esterification of Amino Acids,Chinese Journal of Chemistry

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Electrochemical Dimethyl Sulfide-Mediated Esterification of Amino Acids
Chinese Journal of Chemistry ( IF 5.5 ) Pub Date : 2021-07-26 , DOI: 10.1002/cjoc.202100395
Yongli Li ₁ , Huamin Wang ₁ , Heng Zhang ₁ , Aiwen Lei _{1,

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Affiliation

Dimethyl sulfide-mediated electrochemical synthetic strategy for esterification of amino acids has been reported. A series of amino acids could react smoothly with alcohols, affording the desired esterification products with good efficiency. Importantly, the tolerance of peptides and gram-scale synthesis shed light on the utility of this protocol. Mechanistically, the dimethyl sulfide as a mediator plays an essential role in the transformation of amino acids.