Abstract

Background

Syringe services programs (SSPs) are evidence-based interventions that provide essential overdose and infectious disease prevention resources to people who inject drugs (PWID). Little research has examined factors associated with sterile syringe acquisition at SSPs among rural PWID populations.

Objectives

We aim to identify factors associated with PWID in a rural county in West Virginia having recently acquired sterile syringes at an SSP.

Methods

PWID (n = 420) completed a survey that included measures related to sociodemographics, structural vulnerabilities, and substance use. We used multivariable Poisson regression with robust variance estimation to examine independent associations with sterile syringe acquisition at an SSP.

Results

Sixty-five percent of our sample reported having recently acquired sterile syringes at an SSP. Factors associated with recent sterile syringes acquisition at an SSP included: being older (aPR [adjusted prevalence ratio]: 1.011, 95% CI: 1.003–1.019), single (aPR: 0.862, 95% CI: 0.755–0.984), experiencing food insecurity (aPR: 1.233, 95% CI: 1.062–1.431), recently injecting fentanyl (aPR: 1.178, 95% CI: 1.010–1.375) and prescription opioid pain relievers (aPR: 0.681, 95% CI: 0.551–0.842), and recent naloxone acquisition (aPR: 1.360; 95% CI: 1.178–1.569). Receptive syringe sharing was inversely associated with acquiring sterile syringes at an SSP (aPR: 0.852; 95% CI: 0.741–0.979).

Conclusion

PWID accessing sterile syringes at an SSP was associated with several sociodemographic, structural, and substance use factors. Ensuring rural SSP operations are tailored to local PWID population-level needs is paramount to the prevention of infectious disease outbreaks and overdose fatalities.

中文翻译：

---

与西弗吉尼亚州注射毒品者获得无菌注射器相关的因素

摘要

背景

注射器服务计划 (SSP) 是循证干预措施，可为注射吸毒者 (PWID) 提供必要的过量用药和传染病预防资源。很少有研究调查农村注射吸毒者人群中与在 SSP 处获得无菌注射器相关的因素。

目标

我们的目标是在西弗吉尼亚州的一个农村县确定与 PWID 相关的因素，该县最近在 SSP 获得了无菌注射器。

方法

PWID ( n  = 420) 完成了一项调查，其中包括与社会人口统计学、结构脆弱性和物质使用相关的措施。我们使用具有稳健方差估计的多变量泊松回归来检查与 SSP 处无菌注射器采集的独立关联。

结果

我们的样本中有 65% 报告说最近在 SSP 获得了无菌注射器。与最近在 SSP 处获得无菌注射器相关的因素包括：年龄较大（aPR [调整后患病率]：1.011，95% CI：1.003–1.019）、单身（aPR：0.862、95% CI：0.755–0.984）、经历食物不安全感（aPR：1.233，95% CI：1.062-1.431），最近注射芬太尼（aPR：1.178，95% CI：1.010-1.375）和处方阿片类止痛药（aPR：0.681，955% CI：1-0.0）和最近获得纳洛酮（aPR：1.360；95% CI：1.178–1.569）。接受注射器共享与在 SSP 获得无菌注射器呈负相关（aPR：0.852；95% CI：0.741–0.979）。

结论

PWID 在 SSP 使用无菌注射器与若干社会人口、结构和物质使用因素有关。确保农村 SSP 操作适合当地注射吸毒者人群的需求，这对于预防传染病爆发和过量死亡至关重要。