Abstract

Delivering viable probiotics at adequate doses is essential to exert a beneficial effect on the host organism. However, the viability of probiotics is affected by environmental conditions and biochemical changes during storage and digestion. Drying probiotics into powder form exerts various benefits (e.g. ease of handling, high stability, less space needed for storage, and maintaining cell viability). However, the final product's cell viability and fundamental powder properties are considerably affected by the type of protective material used and the drying technique employed. A comprehensive summary of probiotic drying techniques, protective materials used, mathematical models to predict survival, and powder properties has been discussed in this review. Achievements made using innovative drying methods have also been analyzed.

摘要

以足够的剂量提供可行的益生菌对于对宿主生物体发挥有益作用至关重要。然而，益生菌的活力受储存和消化过程中环境条件和生化变化的影响。将益生菌干燥成粉末形式具有多种好处（例如，易于处理、稳定性高、储存所需的空间更少以及保持细胞活力）。然而，最终产品的细胞活力和基本粉末特性在很大程度上受到所用保护材料类型和所用干燥技术的影响。本综述讨论了益生菌干燥技术、使用的保护材料、预测存活的数学模型和粉末特性的综合总结。还分析了使用创新干燥方法取得的成就。