Abstract

The ability of fucoidans to scavenge reactive oxygen species still remains a subject of debate in scientific literature, as shown by an analysis of the results of recent studies on the antioxidant activity (AOA) of fucoidans. On the one hand, in vitro and in vivo experiments provide evidence that fucoidans of brown algae can modulate diseases associated with oxidative stress by regulating the antioxidant defense systems and signaling pathways. On the other hand, the use of cell-free assay systems has revealed a relationship between the antioxidant activity attributed to fucoidans and the polyphenolic compounds extracted along with them. The polyphenolic compounds of brown algae referred to as phlorotannins are also known as potent antioxidants. Since the vast majority of studies use various commercial preparations or extracts containing fucoidan and polyphenolic compounds without measuring the level of the latter in polysaccharide samples, there is still no clear understanding of whether fucoidans or co-extracted polyphenolic compounds are a priority component providing AOA.

中文翻译：

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褐藻的岩藻多糖可以被视为抗氧化剂吗？

摘要

岩藻依聚糖清除活性氧的能力在科学文献中仍然是一个争论的主题，正如对岩藻依聚糖抗氧化活性 (AOA) 近期研究结果的分析所示。一方面，体外和体内实验提供的证据表明，褐藻的岩藻多糖可以通过调节抗氧化防御系统和信号通路来调节与氧化应激相关的疾病。另一方面，无细胞分析系统的使用揭示了归因于褐藻糖胶的抗氧化活性与与它们一起提取的多酚化合物之间的关系。褐藻的多酚化合物被称为根皮单宁，也被称为强抗氧化剂。