More than a year after its appearance and still rampant around the world, the COVID-19 pandemic has highlighted tragically how poorly the world is prepared to handle systemic risks in an increasingly hyper-connected global social-ecological system. The absence or clear inadequacy of global governance arrangements and mechanisms is painfully distinct and obvious. In this short article, we summarize a set of COVID-19 pandemic-related analyses and lessons that are inspired by Chinese practice. First, strong government response is one of the most important methods to control a pandemic. Second, countries should be concerned about human-to-frozen goods-to-human transmission. Third, sharing resources and experiences through cooperation is crucial to ensure an adequate health response. Based on these insights, we stress the critical importance of coordination and cooperation, and call for a global network to enhance integrated human health risk resilience.