Improved understanding of non-respiratory infections in cystic fibrosis (CF) patients will be vital to sustaining the increased life span of these patients. To date, there has not been a published report of urinary tract infections (UTIs) in CF patients. We performed a retrospective chart review at a major academic medical center during 2010-2020 to determine the features of UTIs in 826 CF patients. We identified 108 UTI episodes during this period. Diabetes, distal intestinal obstruction syndrome (DIOS), and nephrolithiasis were correlated with increased risk of UTIs. UTIs in CF patients were less likely to be caused by Gram-negative rods compared to non-CF patients and more likely to be caused by Enterococcus faecalis. The unique features of UTIs in CF patients highlight the importance of investigating non-respiratory infections to ensure appropriate treatment.

提高对囊性纤维化 (CF) 患者非呼吸道感染的了解对于维持这些患者延长的寿命至关重要。迄今为止，尚无 CF 患者尿路感染 (UTI) 的已发表报告。我们在 2010-2020 年期间在一家主要学术医疗中心进行了回顾性图表审查，以确定 826 名 CF 患者的 UTI 特征。我们在此期间确定了 108 次 UTI 发作。糖尿病、远端肠梗阻综合征 (DIOS) 和肾结石与尿路感染风险增加相关。与非 CF 患者相比，CF 患者的尿路感染不太可能由革兰氏阴性杆菌引起，而更可能由粪肠球菌引起. CF 患者 UTI 的独特特征突出了调查非呼吸道感染以确保适当治疗的重要性。