This study investigated the best way to combine nanofiltration (NF) and Fenton with membrane bioreactor inoculated with Saccharomyces cerevisiae (MBRy) for the treatment of landfill leachate, aiming at compliance with legislation and water reuse. Firstly, the permeate from MBRy was treated by Fenton process followed by NF (MBRy – Fenton – NF). Another alternative evaluated was the polishment of MBRy permeate by NF and treatment of NF concentrate by Fenton process (MBRy – NF – Fenton_{(concentrate)}). COD removal in the Fenton step was optimized according to central composite design (CCD) and 85.5% removal was obtained at pH = 3, Fe²⁺:H₂O₂ molar ratio = 1:9.81 and C:H₂O₂ molar ratio = 1:1.14. Increased toxicity was observed with the Fenton application (EC₅₀ = 2.45%). The NF showed the best performance treating the MBRy permeate. High permeate flux (8.9 ± 1.6 L h⁻¹ m⁻²) and ion rejection (82 ± 4.2%), and low membrane fouling was observed in this condition. Although both NF permeate presented potential for reuse, the final COD concentration was lower in the MBRy – Fenton effluent (88 mg L^-1). The Fenton application for the NF concentrate was able to remove 87.24% of COD. With a preliminary economic analysis, it was verified that the MBRy – NF – Fenton_{(concentrate)} combination is the most advantageous due to the lower chemical reagent and membrane area requirements. Thus, this route presents itself as an alternative for landfill leachate reclamation.

本研究调查了将纳滤 (NF) 和芬顿与接种酿酒酵母(MBRy) 的膜生物反应器结合用于处理垃圾渗滤液的最佳方法，旨在符合法规和水的再利用。首先，MBRy 的渗透物通过 Fenton 工艺处理，然后是 NF（MBRy – Fenton – NF）。评估的另一个替代方案是通过 NF 对 MBRy 渗透液进行抛光，并通过 Fenton 工艺（MBRy – NF – Fenton _{（浓缩物）}）处理 NF 浓缩_物。Fenton 步骤中的 COD 去除率根据中心复合设计 (CCD) 进行了优化，在 pH = 3、Fe ²⁺ :H _{2 条件}下获得了 85.5% 的去除率O ₂摩尔比 = 1:9.81 和 C:H ₂ O ₂摩尔比 = 1:1.14。在芬顿应用中观察到毒性增加（EC ₅₀  = 2.45%）。NF 在处理 MBRy 渗透液时表现出最佳性能。在此条件下观察到高渗透通量 (8.9 ± 1.6 L h ^-1 m ^-2 ) 和离子排斥 (82 ± 4.2%) 和低膜污染。尽管两种 NF 渗透物都具有再利用的潜力，但 MBRy – Fenton 流出物中的最终 COD 浓度较低（88 mg L ^-1）。NF 浓缩物的 Fenton 应用能够去除 87.24% 的 COD。通过初步经济分析，证实 MBRy -由于较低的化学试剂和膜面积要求，NF – Fenton _{（浓缩物）}组合是最有利的。因此，这条路线本身就是垃圾渗滤液回收的替代方案。